There was thick scale over the dorsal aspect of both feet, with diffuse scale involving the soles Figure 2 B. How to cite this article: Suspected medications may be discontinued and switched to an alternative medication when possible, while the psoriasis should be treated according to standard guidelines. This narrative review is based on a nonsystematic literature search in Medline and Embase databases. Paradoxical psoriasis in a large cohort of patients with inflammatory bowel disease receiving treatment with anti-TNF alpha:

Case reports are for a year-old female diagnosed with Crohn’s disease on February after a long history of abdominal pain and bleeding and a year-old female who had psoriatic arthritis with no skin lesions since November Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. Female sex and smoking were more frequently associated with TNF-alpha inhibitor-induced psoriasis. Indian J Dermatol Venereol Leprol. Recognized side effects include immune-mediated toxicity, such as the development of psoriasis. It is noted that the lag time to onset of psoriasis development can take up to 12 months.

New-onset psoriasis in a patient treated with interferon beta-1a. Sign in to customize your interests Sign in to your personal account. She resumed etanercept treatment and continued undergoing topical therapy for her skin disease.

palmoplantar pustular psoriasis induced by adalimumab a case report and literature review

Severe infliximab-induced psoriasis treated with adalimumab switching. The proinflammatory cytokine interferon-alpha produced by plasmacytoid dendritic cells might be implicated. Third, in some cases, the psoriasis flare can persist, even after the suspected drug has been discontinued.


Palmoplantar pustular psoriasis induced by adalimumab: a case report and literature review.

Systemic lupus erythematosus induced by anti-tumour necrosis factor alpha therapy: Mrowietz U, Domm S. In order to provide our website visitors and registered users with a service tailored to their individual preferences we use cookies to analyse visitor traffic and personalise content. Genome-wide expression profiling of five mouse models identifies lnduced and differences with human psoriasis. Home Journals Why publish with us?

Drug-induced psoriasis: clinical perspectives

There is mounting evidence that a key innate immune pathway for triggering common human autoimmune disease, including psoriasis, involves plasmacytoid dendritic cell precursors PDCs and type 1 interferon IFN production. Sody E, Korber A.

Psoriasis provoked or exacerbated by medications: Skin disease developed in 11 patients undergoing treatment with etanercept, 24 taking infliximab, and 8 taking adalimumab. Data were available for 21 women and 11 men, ranging in age from 19 to 69 years data unavailable for the other 11 patients. Synthetic antimalarial drugs and the triggering of psoriasis — do we need disease-specific guidelines for the management of patients with psoriasis at risk of malaria?

One patient required psoralen UV-A therapy to control her psoriasis, and another used acitretin in combination with topical therapy. Immunohistochemical staining was performed using an avidin-biotin peroxidase system Vector Laboratories, Burlington, Ontario after antigen retrieval by microwave pretreatment.

J Korean Med Sci. Ann Rheum Dis ;63 suppl Google Scholar.


There have been documented cases of generalized psoriasis and erythrodermic psoriasis, requiring hospitalization for proper management. Pustular psoriasis induced by hydroxychloroquine: Exacerbation of psoriasis induced by interferon-alpha treatment for melanoma. Create a free personal account to access your subscriptions, sign up for alerts, and more.

Palmoplantar pustular psoriasis induced by adalimumab: a case report and literature review.

Lithium, antipsychotics, and risk of psoriasis. Informed consent was obtained from all patients prior to routine skin biopsy procedures. Psoriasis and increased drug utilization: Paraffin-embedded sections were deparaffinized and stained with standard hematoxylin-eosin.

palmoplantar pustular psoriasis induced by adalimumab a case report and literature review

Lithium, which is prescribed for manic depressive disorders, has been associated with an increased risk for psoriasis development. Editor who approved x In this regard, 1 of our patients patient 7 had both a psoriasiform eruption and evidence of lupuslike autoimmunity. Psoriatic erythroderma caused by terbinafine: Fierlbeck G, Rassner G. Tumor necrosis factor-alpha inhibitor-induced psoriasis: Increased overall drug utilization in patients with psoriasis: The development of psoriasis of the skin in a patient with a rheumatologic disease does not necessarily mean that a misdiagnosis of the rheumatologic condition has been made.