The apical root canal microbiota is predominantly anaerobic and the time of infection can influence this dominance, i. Cultivable bacteria in infected root canals as identified by 16S rRNA gene sequencing. PCR-based identification of bacteria associated with endodontic infections. Corresponding figures for primary infections associated with acute apical abscesses are shown in the next section. Community profiling analyses of the endodontic microbiota have disclosed some interesting findings: The amount of items that can be exported at once is similarly restricted as the full export.

Microbiologic analysis of teeth with failed endodontic treatment and the outcome of conservative re-treatment. This indicates that, even if total bacterial elimination is not the case, at least a substantial reduction in species richness and abundance is attained. However, limitations in culturing techniques, including low sensitivity and inability to detect as-yet-uncultivated bacteria, put the validity of its use as outcome predictor in question. It is reasonable to realize that disease severity, based on intensity of signs and symptoms, or response to treatment may be related to the bacterial community composition. All who received treatment on a tooth with a periapical radiolucency in the Postgraduate Endodontics Clinic, University of Maryland School of Dentistry were invited for a two to five-year follow-up examination. In another study, Siqueira et al.

The microbiota involved with abscesses is mixed and dominated by anaerobic bacteria 19264669 So far, virtually all studies involved with phenotypic or genotypic identification of endodontic bacteria have followed a cross-sectional design, for obvious ethical reasons. However, in some specific circumstances, microorganisms may overcome this defense barrier and establish an extraradicular infection, which can be conceivably dependent on or independent of the intraradicular infection Community profiling analyses of the endodontic microbiota have disclosed some interesting findings: Information provided by these methods has the potential to disclose patterns of molecules associated with diverse clinical conditions, helping establish outcome predictors based not only in specific species combinations or communities, but perhaps even more importantly on the resultant products of these consortia.


However, while there is no reason based on solid scientific evidence to consider an infected canal as a focus of infection to distant body sites, except for systemically compromised patients, the opposite should not be disregarded either, as there is no clear evidence to consider endodontic infections as segregate events with no effect on the rest of the body. The antibacterial action of sodium hypochlorite and EDTA in 60 cases of endodontic therapy. However, there is no direct evidence showing that extraradicular bacteria were actually established as an extradicular infection independent of the intraradicular infection.

Bacteriologic features and antimicrobial susceptibility in isolates from orofacial odontogenic infections. Gram-positive bacteria are more frequently present and include Streptococcus species, P.

dissertation apical periodontitis

As MR1 presents microbial riboflavin metabolite antigens, and CD1d presents endogenous or microbial glycolipid antigens, MAIT cells and iNKT cells survey the non-protein fraction of the potential antigenic universe. Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach. In Sweden the dentists devote around 10X of their total time to treating this disease. This article has been cited by other articles in PMC. The objectives of this thesis were to describe endodontic status in Swedish populations, to study clinical and socio-economic risk factors for apical peiodontitis AP and to explore a possible association between AP and coronary heart disease CHD.

Investigation of bacterial communities associated with asymptomatic and symptomatic endodontic infections by denaturing gradient gel electrophoresis fingerprinting approach.

Microbial involvement with treatment failures is supported by two strong evidence-based arguments. Healing was determined using the periapical index.

Distinctive features of the microbiota associated with different forms of apical periodontitis

Show downloadable dissertations only. Acute apical periodontitis and abscesses Acute apical periodontitis and acute apical abscesses are typical acute forms of apical periodontitis. Denaturing gradient gel electrophoresis perriodontitis of bacterial communities associated with failed endodontic treatment. Direct amplification of rRNA gene sequences for identification of selected oral pathogens in root canal infections.


dissertation apical periodontitis

Predominant indigenous oral bacteria isolated from infected root canals after varied times of closure. Staphylococcus epidermidis and Staphylococcus xylosus in a secondary root canal infection with persistent symptoms: Apical actinomycosis, which is caused by Actinomyces species or P.

The Association of Statin Intake and Healing of Apical Periodontitis After Root Canal Treatment

Bacterial reduction and persistence after endodontic treatment procedures. PCR-based identification of bacteria associated with endodontic infections.

Other bacteria found in root canal-treated teeth with apical periodontitis include Streptococcus species and some fastidious anaerobic species xissertation P. Quantitative open-ended molecular methods that are more sensitive than culture have the potential to establish more reliable standards to predict outcome. Intraradicular bacteria and fungi in root-filled, asymptomatic human teeth with therapy-resistant periapical lesions: Herpesviruses in endodontic pathoses: Demonstration of Bacteroides intermedius in periapical tissue using indirect immunofluorescence microscopy.

Distinctive features of the microbiota associated with different forms of apical periodontitis

Abstract The aim of this study was to analyze the association between statin periodongitis and apical periodontitis healing after root canal treatment. While association of E. Author information Article notes Copyright and License information Disclaimer. Polymerase chain reaction-based analysis of microorganisms associated with failed endodontic treatment.

As for the lesion specimens, bacteria were not detected in six cases